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Protein expression services for gars-1 | Glycine--tRNA ligase

Description
Catalyzes the ATP-dependent ligation of glycine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (Gly-AMP). Also produces diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. Thereby, may play a special role in Ap4A homeostasis.
Family
Belongs to the class-II aminoacyl-tRNA synthetase family.
Species
Caenorhabditis elegans
Length
742 amino acids
Sequence
MFSSCWLKSSVRYSRLIRQFSSENSFFKVELVPSDRKTPLQPRKVVAPRFEKKTRQKISDYLKQMATPEIEAKLAPLRAAVKEYGDLIRDLKAKGAPKIDIDKAVVELKARKRLLEDTEIALAPKEASFDRLKLEDLLKRRFFYDQSFAIYGGVTGLYDFGPMGCSLKANMLQEWRKHFILEEGMLEVDCTSLTPEPVLKASGHVDRFADWMVKDMKNGECFRADHLIKNSIEKLLNDKKTSAAVKQDGQDVLARLEGFDNKDMHEVITRFNFKSPITGNDLTEPIAFNLMFPTQIGPTGDFKAFLRPETAQGIFVNFKRLLEFNQGKLPFAAAQIGLGFRNEISPRQGLIRVREFTMCEIEHFVDPEDKSLAKFAKVADQKLVLFSACNQLDGAPAQEVAIGEAVAKKTVANETLGYYMARCHQFLMKVGIDGRRLRFRQHLSNEMAHYAQDCWDAEILTSYGWIECVGNADRACYDLQQHYKATNVKLVAEKKLPEPVDVNFVEAQANMALLGKSFKKDAKKIQTSLQQLTSEQVSALEEELLAKKLYNLSVDGQNYALTPEHLNIKKYTKKIHVQEITPSVIEPSYGIGRIMYALLEHSFRQREGDEQRTFLAFKPLVAPIKCSVLPISANDTLIPVMDAVKEELSRFEMSYKVDDSSGTIGRRYARTDEIGIPFGITVDFDSLKTTPFTVTIRHAETMSQIRLEVSELGRLISDLVAGRQQWSDAQAKYPKFEASATE
Mass
84.2 kDa
Simulated SDS-PAGE
Western blot of gars-1 recombinant protein(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service
Make gars-1 using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)

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