Description
Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation (By similarity).
Family
Belongs to the glutaminyl-peptide cyclotransferase family.
Sequence
MARERRDSKAATFFCLAWALCLALPGYPQHVSGREDRADWTQEKYSHRPTILNATCILQVTSQTNVSRMWQNDLHPILIERYPGSPGSYAVRQHIKHRLQGLQAGWLVEEDTFQSHTPYGYRTFSNIISTLNPLAKRHLVIACHYDSKYFPPQLDGKVFVGATDSAVPCAMMLELARSLDRPLSFLKQSSLPPKADLSLKLIFFDGEEAFVRWSPSDSLYGSRSLAQKMASTPHPPGARNTYQIRGIDLFVLLDLIGARNPVFPVYFLNTARWFGRLEAIERNLNDLGLLNNYSSERQYFRSNLRRHPVEDDHIPFLRRGVPILHLIPSPFPRVWHTMEDNEENLDKPTIDNLSKILQVFVLEYLNLG
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service