Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).

Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.

445 amino acids

MTHPVVRFAPSPTGRLHVGNVRTALINWMFSRGQQGKFILRIDDTDLERSTAEHEEALKVDLTWLGLTWDDSFSQSHRFANYDAAADKLRALHLLYPCYETAEELDVKRKIAQTRGRPPVYDRAALSLTAQDRADLEAKGRKPHWRFKLSGERVEWNDLVRGPQSIDTASVSDPILIREDGSYLYTLPSVVDDIEAGITHVVRGEDHVTNSGAQIEIFMALGGKAPEMAHTPLLIGADGAALSKRIGSLSMGELRARGYEPMAICSHLAKLGTSDNIEARATLEQLCEEFSFSKIGRAPARFDDNDLNALNAALVHAMPFEAVRERLITLDARAASEPFWLAVRENCTFVADAISWVDMVYGSPAPLVAEEDREFISGAAMYLPEGELTTESWSAWTNALKAATGRKGRGLFMPLRKALTGAEHGPEMSAVLPLIGREKVLQRLS

49.2 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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