Protein expression services for gcs-1 | Glutamate--cysteine ligase
Description
Plays a role in resistance to arsenite (PubMed:23593298). May play a role in the oxidative stress response induced by reactive oxygen species produced during infection by pathogenic bacteria (PubMed:22216003). Together with trxr-1, required for the reduction of disulfide groups in the cuticle during molting (PubMed:21199936).
Family
Belongs to the glutamate--cysteine ligase type 3 family.
Species
Caenorhabditis elegans
Length
654 amino acids
Sequence
MGLLTKGSPLTWAETVPHIDYIKKHGIAQFINLYHRLKSRHGDQLKWGDEIEYTIVKFDDANKKVRVSCKAEELLNKLQAEEQVNAMLGTANRFLWRPEFGSYMIEGTPGMPYGGLIACFNIVEANMKLRRQVVKKLLKKDETCLSISFPSLGVPGFTFPEVAADRKNDDAANSVFWPEQAVFLGHPRFKNLTKNIKGRRGSKVAINVPIFKDTNTPSPFVEDLSALGGPDDTRDAKPDHIYMDHMGFGMGCCCLQVTFQAVNVDEARWLYDQLTPITPILLALSAATPIFRGKLSNVDSRWDIISASVDDRTPEERGLEPLKNSKWVIDKSRYDSTDCYIYPCSVGYNDIPLQYDETIYKQLIDGNIDEPLAKHIAHMFIRDPHQVFRERIEQDDEKSSEHFETIQSSNWMNMRFKPPPPDAPEIGWRVEFRPTEVQLTDFENAAYCCFVVLLTRMMISFRLTYLMPISMVTENMKRAQQKDAVLNQKFLFRKGLAECKSAPENLKGSEKCGPPSQDIEEMSIDEIINGKKNGFPGLISLIRQFLDSADVDVDTRCTISQYLNFISKRATGEINTLAHWTRGFVQSHPAYKHDSDVNDNIVYDLLKKMDAISNGEDHCEKLLGCYRSKTDHAISAAVRKAEEHMIVSSQKRAH
Mass
74.4 kDa
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)Safety
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