L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of glutamate are mediated by a variety of receptors that are named according to their selective agonists. Required for response to mechanical and osmotic stimuli.

Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.

977 amino acids

MNKNLLVFGFLIFVKIGETSKKFPLRAFVASTDIDNDTAHAIIEMLRLAEMTFNALSDVDFDVLLGTRDLPPMEMATMMWNLNRIICDEMKLGYMLMLAGTNFKNYGIYEDIANHMKMPLIDWEPSKSENIGKTTENNPMIFSVAPSAEQLLIDYIQYKGWRDVVYIHDGKNADRTLRTMFSYLHEKSPKYQLFVDNYVAPSDEEMFKEFLNEFHRRISTQHTLKSNDSSEEIDEPIPVNVIVDLEGSYRTRAFLRALEESVLVKKEYHYVFSNFDVDETDLSGFHFSLINITIFRIFDKNNKKFLKTRAEFHDVYRGGFSNTDSIPTAAAFAHDAILVAGKALQIAMNEHGKGIFDKSFVRHQLFNRGRKGLYCRPHEDQTESRQFETFEHGKKIAEAIKKVVLTDKDGTLTGRIQFDKVTGKRTNFSAEIVEIKPGVNSLNSIWERFQWAEGEGFLLGGERYVQEKKKDSSQTRKGILPSKPWQLRFNVVTVLVKPFVMLKRRNPGEPELKGNDRFEGYCIDLLNLLAKNITGFEYDVFISDGNKYGSRQADGSWDGMIGYLLNETADVAVAPLTITQERERAVDFSKPFMTTGISIMIKKPEKQEFNIFSFMEPLGMTIWIFTLSSYFGVSLTIFLVSWFSPYEKRIEFKRGEFTVTNEFTLYNSLWFTLAAFMQQGTDILPRAVSGRIASSCWWFFTLIIVSSYTANLAAFLTLERMTPPIESVEDLANQNKILYGVNEGGSTAAFFEDSIVPLYKKMWNFMVSTTQKQIELEKQSITNSTSNRIFVSSYADGIEKVRTSKGKYAFLLEETTNNYESGRRPCDTMKVGQNLNTLGYGIATKIGNPLRVSLNLAILYLSEKGELKKLENKWWYDRGQCDTGTSDGGTSSSLNLSKVAGIFYILLAGMVLSMCTALVEFLFRKNKENREKERNRMRSSRPLKPGILASCERAKQKQLQNRRTKSEEVSTPRSTLF

111.8 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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