Description
Catalyzes the oxygen-dependent ring fission of gentisate between the carboxyl and proximal hydroxyl groups at positions 1 and 2 of the aromatic ring to form maleylpyruvate. No activity with cathechol and protecatechuate as substrates. Part of a 3-hydroxybenzoic acid-degradation pathway.
Family
Belongs to the gentisate 1,2-dioxygenase family.
Sequence
MAEQEPKELLEMSTDTERLLEENDLRPLWEVEKDFGNQFGGFEADIWKWEDIQASIDAIERDVPIADLPPGFQRRVAVPVNTGYRNAISNTIYVGVQTVSPGETAPAHRHGANALRFTIDGSEDMKTVVAGEEFPMRDNDLITTPQWEWHDHVNDGDETAAWLDVLDLPLVLDSLNARNTFENHELDRQPVTKSQGYWESQYGRARPFEDTKEDGIPGPFEGNCAATPPYRFSWKDTLQTLRQRAENDDPDPHDGYSLSYVNPATGQPPLFPTMSFRAQLLQEETDPHFHNAVDAYFVIEGEGATHVGDDVLEWSERDIFVIPPDEIHHHDPDGEAILLGMTDRPVFEAFNFYAEAEP
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service