TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

Belongs to the TFIIF alpha subunit family.

577 amino acids

MSSASKSTPSAASGSSTSAAAAAAASVASGSASSSANVQEFKIRVPKMPKKHHVMRFNATLNVDFAQWRNVKLERENNMKEFRGMEEDQPKFGAGSEYNRDQREEARRKKFGIIARKYRPEAQPWILKVGGKTGKKFKGIREGGVGENAAFYVFTHAPDGAIEAYPLTEWYNFQPIQRYKSLSAEEAEQEFGRRKKVMNYFSLMLRKRLRGDEEEEQDPEEAKLIKAATKKSKELKITDMDEWIDSEDESDSEDEEDKKKKEQEDSDDGKAKGKGKKGADKKKKKRDVDDEAFEESDDGDEEGREMDYDTSSSEDEPDPEAKVDKDMKGVAEEDALRKLLTSDEEEDDEKKSDESDKEDADGEKKKKDKGKDEVSKDKKKKKPTKDDKKGKSNGSGDSSTDFSSDSTDSEDDLSNGPPKKKVVVKDKDKEKEKEKESAASSKVIASSSNANKSRSATPTLSTDASKRKMNSLPSDLTASDTSNSPTSTPAKRPKNEISTSLPTSFSGGKVEDYGITEEAVRRYLKRKPLTATELLTKFKNKKTPVSSDRLVETMTKILKKINPVKHTIQGKMYLWIK

64.5 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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