Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction. Mediates interaction with intestinal microbiota influencing its composition. Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen, which is an essential substrate for the final step in the membrane-associated blood group antigen synthesis pathway.

344 amino acids

MFSTQTFFFFPTAPFILFVFTASTIFHLHQRLEKMQPTWELEALEPATMETPSRPQPRPQLKGMWTINAIGRLGNQMGEYATLYALAKMNGRAAFIPPQMHSTLAPIFRITLPVLHDATARSVPWQNYHLNDWMEEQYRHIPGEYVRLTGYPCSWTFYHHLRAEILQEFTLHAHVREEAQNFLRGLRVNGSRPSTYVGVHVRRGDYVHVMPNVWKGVVADRRYLEQALDWFRARYSAPIFVVSSNGMAWCRENINASRGDVVFAGNGNEGSPAKDFALLTQCNHTIMTIGTFGIWAAYLAGGETIYLANYTLPDSPFLKIFKPEAAFLPKWIGIPADLSPLLKH

39.3 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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