Description
Acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF), and participates in various processes such as endocytosis, insulin receptor internalization or LC2A4/GLUT4 trafficking.
Family
Belongs to the GAPVD1 family.
Sequence
MVKPDIHTLAHHLKQERLYVNSEKQLIQRLNADLLKTAERLYRTSWIAKQQRINLDRLILTSAEASPAECCQHAKVLEDTQFVDGYKQLGFQETAYGEFLNLLRENPRLIASCLVTGEKLNQENAQSVIHTVFTSLYGNCIMQEDESYLLQVLRYLIEFELKESDNPRRLLRKGTCAFSIIFKLFSEGLFSAKLFLTATLHEPIMQLLVEDEDHLETDPAKLIERFSPAQQEKLFGGKGTEAFRQRVQAMVETNEAKLVALVNKFIGYLKQNTYCFPHSLRWIVSQMFKTLSCVEGLEVSEVRSMCTDLLLTCFICPAIVNPEQYGIISDAPINEVARFNLMQVGRLLQQLALTGFEERDSRNKSNLNKFDKSCVAAFLDVVIGGRAVETPPLSSVNLLEGLSRTVVYMTYSQLMSLLGFMRTVISSEQLQEEDRMALENLLATVPQTKPGKSNNDTPYSTPQLSPATTPACKKNRLPIVTRSRSKTNLMETENECSPQEVTPNQPEEVLVISLGTGPQLTPGMMSENEVLNMQLVDGGQGDVPVDESKLHGKPDKTLRFSLCSDNLEGISEEEENPCSTGPSNRSNSVSSLDLEGESVSELGGGPSGSNGVEALQLLEHEQATTQDNLDDKLRKFEIRDMMGLTDDRDISETVSETWSTDVLGSDFDPNIDEDRLQEIAGAAAENMLGSLLCLPGSLLLDPCTISETTSEAWSVEVLPSDSAPDLKQEERLHELESCSGLGSTSDDTEVREVSSRPSTPGLSVVSGISATSEDIPNKTEDLRSECSSDFGGKDSVTSPEAEESVHGPHHITTPPTQSESLLAMFDPLAPASSEVVRPKVHYARPSHPPPDPPVLEGASGGNEARLPMFCSHVFIHTDSEAYRQRHSCPERLVRSRSSDIASSIRRPISDPGWVRRGINEDRELLTGTAVNALINPPQSSSFSPSKDSSRGEPDEKKDSDDERSDRNKPWWKKRFVSAMPKAPIPFRKKEKQEKEREDFVQDRFYVAVDSTSQLGPHSQAAEDILAKYRNAIKRTIPNEGSTMPYEGADPVGDGESLHESPRDEALQNMTSDDLLDSANQVAHPQESAFSYRDAKKKLRLALCSADSVAFPVLSHSTRNGLPDHTDPEDNEIVCFLKVQLAEAINLQDKNLMAQIQETMRCVSRFDSRSCSKILSSLAEDYRKRASYIAYLTRCRQGLQSTQAHLDRLLQRVLRDKEVSTRYFTTVCVRLLLESKENEIHEFIQDFQKLTAADDKTAQVEEFLQSLYGAMAQDVIWQNASEEQLQDAQIAIERSIMNRIFKLAFNPNQDADILRDQVLHEHIKRLSKVVTANHRALQIPEVYLREAPWPSAQTEIRTISAYKTPRDKVQCILRMCSTIMNLLSLANEYSVPGADDFVPVLVFVLIKANPTYLLSTVQYISSFYSNRLIGEESYWWMQFTAAVEFIKTIDDRK
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service