Description
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
Family
Belongs to the thymidylate synthase ThyX family.
Species
Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W)
Sequence
MTVTLMQHTSLTICAHAIRTCWQSFEKSDGGGEKDRELIDRVGNKNKHASTLEHLVYTFYIQGISRACLQELARHRIASLSVKSSRYTLKELKAEEEFKEGDWERAKRYLVETESEAVNLASLKALENLRQVLLLGISNDMAKYCLPESYKTELTWTINARALQNFLTLRSSKSALWEIRKLAKTLHEALPKEHRYLFCLNQEG
Simulated SDS-PAGE

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service