Description
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
Family
Belongs to the thymidylate synthase ThyX family.
Species
Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)
Sequence
MVILETPRVFLIASWGSEAVISAFTDALYRGVPWEEAVKAQAPDVIIKRISAFYRQGHWSVFEFMGAQFLVECSRACHTQFIRHRMASYWSESQRYVDYTKREIRFVVPKGFPADLLKRAYEDYARLREGFRPEYARMILPNATAVLFAVQMNARELLLNFAPLRCAYAAQAEIRHVCWQMFAHAWRLWPNLARLVWEDLPSLHRDFCTKVPRGEDCRLYAIKDAEEKHGPLPETPWLSALVHG
Simulated SDS-PAGE

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service