Description
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
Family
Belongs to the thymidylate synthase ThyX family.
Species
Mycobacterium abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543)
Sequence
MAEIVPLRVQLIAKTDFIAPPDIDWSTDADGGPALVEFAGRACYQSWSKPNPRTATNESYLRHVIEVGHLSVLEHASATFYITGISRSCTHELIRHRHFSYSQLSQRFVPEDDSNVVLPPAVEDDPELVALVRKATDASRAAYVELLEKLESTLADVPNAVLRRKQARQAARSVLPNATETRIVVTGNYRAWRHFIAMRASEHADVEIRRLAIACLRQLADLAPSIFGDFDIATLADGTEVAISPLVYEG
Simulated SDS-PAGE

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service