Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.

In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

714 amino acids

MDMTSAFTLNVRLDHIAVVTIDVPGEKMNTLKAEFAAQVRAILKEIRENKEIRGVVFISAKADNFIAGADINMIDHCNTAMEAETLARQGQQLMAEIHALPVPVIAAIHGACLGGGLELALACHGRICTDDPKTILGLPEVQLGLLPGSGGTQRLPRLVGLSTALDMILTGKQLRPGQALKSGLVDEIVPQSILLQAAVERAKQERQTPRSLPVRERILAGPLGRSLLFRFVSKKTDQKTQGNYPATTRILDVIETGLSQGSSSGYDAEARAFGELAMTSQSQSLRNIFFASTEVKKDPGSTVQPGTLDSIGILGGGLMGGGIAFVTACKAGLPVRIKDINPQGINHALKYSWQLLDAKVRRRHIKAGEQARQLAKISGTTDYQGFAHRDVVIEAVFEDLSLKQQMVAEVEKNCGLHTIFASNTSSIPISDIAAHATRPEQVIGLHFFSPVEKMPLVEVIPHAATSEKTIATIVKLAKKQGKTPIVVQDKAGFYVNRILAPYINEAIRLLTEGEKVETIDTALVKFGFPVGPIQLLDEVGIDTGTKIIPVLEAAYGERFSAPANVVSSILNDDRKGRKNGRGFYLYGAKGRKSKKQVDPEIYKIIAVQGQSKLSAQQITERCVMLMLNEAARCYREGVIRHARDGDIGAVFGIGFPPFLGGPFRYMDSLGASEVVAVLQRLTSLYGSRFTPCEQLLQMAERGESFWKTSATDRH

77.4 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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