Single strand DNA specific 5' exonuclease involved in mitochondrial DNA replication and recombination. Releases dinucleotides as main products of catalysis. Has the capacity to slide across 5'double-stranded DNA or 5'RNA sequences and resumes cutting two nucleotides downstream of the double-stranded-to-single-stranded junction or RNA-to-DNA junction, respectively (By similarity).

Belongs to the EXO5 family.

630 amino acids

MIRPGKVLVLNFLKRSLSNLATFKGSEINTKKYDLKLPNNSDSNKQYFTLDEKLKVIQYTDANEESIIDEFILPLSSGAKASDTYQKTNLSKMRNLLTTFHIDEGESLPLSKPGYIKETPFEYHSKYNSDTSYVSIPRLSVTKLLTFQWCELREFYTIFSGSPVKKETKEMKLGTEAHLKLELETHNLIDVEDIERITDEFVEKKIDSSKRHINTLADPDDILLAKDDLSKLTELLHGAIPESSMANEWMSKIISRLFTLINTSEAREVLVHGYLDFQTSHFTSNLHDFQLNQSNLVLVSGVVDYLKLFNPHDKTDYSMFEDIQDHVEFTYSSQRKHQWIDLSQFLKDIDPIIKEYSDTYKIAITDVKTRSWNKLPQQESVLQAAKLQVEYYRNMFGILAGEFDDIEIGYEMLLENAKRRNLDVDKPISIKSALALLKANHTIILKDYVKLANGEAIGFESFDRFSQERYLNQGSEYDFTKVLEGTNREDYISQIKASDKDGFDFDEILTSDILKAWKIPLTLRYFAARSSQLFHLCKPFLSDSLSIEYHNVKKNDQCFHTNYYNYNANEIDEVTAKASAFWNGTRPPIPVQDLSKCNYCDFSSRCVIPNPHKNVPGSYGSVGSKMKHFI

72.6 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.

Make EXO5 using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)

Order Here