Protein expression services for exo1 | Exonuclease 1
Description
5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment (By similarity).
Family
Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
Species
Dictyostelium discoideum
Length
1046 amino acids
Sequence
MGISGLLPALSPVTKAIHVKDYANKRVAIDGYSWLHKGAYSCSQEIVLGIPTRNYINYFISRIKMLISYKVIPVVIFDGGPLPNKKLKEQERLRHREEYKNKAKAYLLEGNKSQANICFQKAVDITPRMAFLLIKELRALKVEYLVAPYEADAQLTYLSITGQVDAIITEDSDLVAFGATHIIFKMDKYGYAQEIKTEDLGSCKKDGYDFIDFNQTMLRQMCILSGCDYLPSLSGMGLKTSFKLLKQHRDIEKVFKYLKREKSNFSQEYEQQFYKADFTFKHQRVFDPVSRILTTLLPLPTIIDSRFLNDNNNNTNDGDSNGDGSSGGSGSGGGFLDFIGPVIDDEIAEKIALGIIDPETHEQFDKTQPYPKNTFTPQPKKLLSPISFNTKEFKNQTNNNNNNNNNIKSNNGTNNKNGMILNEGKLVQKGRNLNDQFTFASNKITQYMTTTTTTTTTTTTTKNNNNNQKQQPMIEDDTGYDFQIDSFEIDDCLNDDDDDESIILSNNLNNQENVLESDCEFDDDDDQRGIDVDDSEKKDSFVLDSDYEDEKEEEEVKSSTFNSSSSISSGNSSKIKKTLVSSKFFVSSESSVLESDDDDGGDDDDDSFNHNQNFSSSGNNIQPNSNIFHNGELSSYGYQKNQKNFKNVNSNSSSNSSNSSNSSSGNSNSGNRIFNSGNSSNKNNTNGGIVKSTLLSSNDRVSLNFFDQFQFDGKKKQSILVSQSRKSFSSPTLSNNEDYDSSFVSSTIPSSIGDDYDQMNSCSNNNNFNYNNSSNFNNNNINNSNNNRNSGFSGFLKRKSSSQTAAPTTPTTPTTPKTSSSSSSTLTNSTITTEHSSYILKKPKYQATSNSPISTLDSSQNYNDQSFISKKAHSFSSLDSDLIFKEDDVDNLIFNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNDNNNKITTPSNKSFNSIVLTTTSATTSITQQDNEIYTTPKKKLPSTPISSSSNDIISKYFSSPSKVGPKSEGAPPTPVNLEGMSLRSVLSLRYQQTMASSPTK
Mass
116.4 kDa
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service
Make exo1 using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)
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