Putative 5'->3' double-stranded DNA exonuclease which may also contain a cryptic 3'->5' double-stranded DNA exonuclease activity. May be involved in DNA mismatch repair (MMR) (By similarity).

Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.

735 amino acids

MGIQGLLPLLKSIMVPIHIKELEGCIVAVDTYSWLHKGALSCSRELCKGLPTKRHIQYCMHRVNLLRHHGVKPIMVFDGGPLPMKLEQENKRARSRKENLARALEHEANGNSSAAYECYSKAVDISPSIAHELIQVLRQENVDYVVAPYEADAQMAFLAITKQVDAIITEDSDLIPFGCLRIIFKMDKFGHGVEFQASKLPKNKDLSLSGFSSQMLLEMCILSGCDYLQSLPGMGLKRAHALITKFKSYDRVIKHLKYSTVSVPPLYEESFKRALLTFKHQRVYDPNAEDIIHLCDISDNLGEDSDFVGPSMPQDIAKGIALGQLDPFTQLPFQAESVTPKLAVDDISRPKSFKPETVKKKLDLPVQKNLLTKYFCFASVEAKRKFKAPRISPMSLTPTDESPSIPDDNTPDLDALSSQTTNESPVYSLGENPCVSEVAEKRDSPDDDAVERNHKDLHHKYCEREVDRPKSDSLKVIVRSKYFKQKQEDKSLKQSIPCLNDCSVIGQRKAVKTVINMSSASKREESHRAIATSPCLHHDRIYNDHEDAKEASFSAMNEVAERTINTHKINHQINEEEQNPSVEIPSAFSTPENVIPLSSIAIDSCHGVATGKRKLDSDENLHKENLKSKHMRMDETDTALNAETPLETDDVEKFGSNISHIGHYSEIAEKSVERFVSAISSFKYSGTGSRASGLRAPLKDIRNTCPSKGLSLKPDISKFGYASSNRHMVTKSRRM

82.2 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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