Description
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Family
Belongs to the eIF-3 subunit A family.
Species
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)
Sequence
MAPPHRHHNFRPENVYKRAEDLIAVGQRNAALETLYELITSKRIRYLAVQDLEPIALLLIELAVDLRKGKLAKDALHQYKKNVQLSENGLESVQVIVRKFIELAEKKLEEAQAKADVKIDQGEVEDLEAAQTPESILLSAVSNADSADRTERELVNPWLRFLWEALRAVLDILRNNSKLEVTYSAIVNQAFQFCLKFNRKAEFRRLCELLRGHMQSVTTQIKPTGSMNAIDLSDSETVQRYLDQRFAQLNISVKLELWQESFRSVDDVHTLITASKKAPRPVMMANYYENLGRIFAVSGNSLYHAAAWNKFFNLYCQSPNATDDELSHYASILVLATLSVPQKSLNSNETVVDDHKAKNAKLTSLLNLNQVPTRDTLLKSIVSRSILSFVDPAVKQLFTVLEEDEFHPLTIKKKVSEVFQLIESNKDYKQYIPTLTEAILIRLYQQVSQVYETVKLDFLVSLGIIEGTEFSLSALEVENLIVNGVKDGHLSLTIDHETDVVTLKSKPFEDAFTDSLTSKLQISPSELVRSQLSKLAQTLSSSAKVIDPEYEVRIQKTRNEALKNAIADMAREQQEIADRVNVMEERKRIADKAKREQDEEAARLRQEANVAEQKAEQERILAEQERRNLEKLERERQLVKEKEKLKIAEEINAKGIIKLDLNNLDDLDTEKLRIMQIEQLNKDKKDLEERLKVLSKKNDHTERAFRRYELQYLEKDAEKQQEDDIKNYETLKELKISKAKKDHEESLALKDRLQRIVPDFEPFKKIIDEKHSSKLAELRKEAQAALEQAKRERTERVKHQRMDELMERREYERKEAEQEEIKRKRQEEMDKFKEELRIQKEKDADSLRRRQEMANESAKPATPEPVPAPVPAAAAAAAKPSAPLTFAEKMRLKRLGKPGN
Simulated SDS-PAGE
![Western blot of TIF32 recombinant protein](/recombinant/TIF32-21.png)
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service