RING-finger E3 ubiquitin ligase which catalyzes the formation of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Plays an important role in virulence by acting as an anti-apoptotic factor.

Belongs to the poxviridae p28 protein family.

242 amino acids

MEFDPTKINISSIDHVTILQYIDEPNDIRLTVCIIQNINNITYYINITKINPHLANQFRTWKKRIAGRDYMTNLSRDTGIQQSKLTETIRNCQKNRNIYGLYIHYNLVINVVIDWITDVIVQSILRGLVNWYIANNNYTPNTPNNTTTISELDIIKILDKYEEVYRVSKEKECGICYEVVYSKRLENDRYFGLLDSCNHIFCITCINIWHRTRRETGASDNCPICRTRFRNITMSKFYKLVN

28.6 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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