Protein expression services for rkr1 | E3 ubiquitin-protein ligase listerin
Description
E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Ubiquitination leads to cdc48 recruitment for extraction and degradation of the incomplete translation product.
Family
Belongs to the LTN1 family.
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
1610 amino acids
Sequence
MKKKSTDLYGRKNPGMQSMSGSFSSLQIALDESSSNFSTIYEPPDLSGLDAEMIVIVKNLQKRDIVTKCRALQDLIQWNDPSQFDNEQFLNALAVLFPRLSIEVERHVRLKIFVFMSVLSSALQKKLAPWLKFYITPWVMGFFDSDRAVSVSAKDSFKNLLSEEKWPHVWLKFGSTIAPIVTDVFLHEDKESLTDLRFFSNEEAESKVTRVKSSCLLTLSFLFKQTADLENLETDKKIDKQTFKSSLYENLSTLFKSDEFWSLVSSPQDGVTVSLSDLLLIILKYDKPFVTQYKEKYFKRVSRMISRLTSLTCVPMLRLLSNMISNFPNEVHQFANDSKRPLSKLFSNLITKRISLPNSGFYTSLLNLFKSIGAMQLVPSIESVDELCDAFLETANQEQRFLSTEVYDCLLNFLSFVYTDSSDPQIKDHVRDRLRTIFTRYFKGEFVLRCSTSDFDHCLQSVFDKNSDFASLWNEVLFGFFNDESMDIETIPFDSLSRNLSLTVQTVLYLKNRNFQTGNEVMSILGPCLSFLMKLSTHKNERIACLSASQLITVCHIFSDTTLIKPVKELFQKYLVNDLPSSILKLGPQSPAFTLLRDILLLLKDYADLSEPWENVANQFTVSFDELENIRVLNSLPSLFADGKLRGKISLVKTLVEYYDTAVFAIMQNPGNDWDMIRACIGSKEILVPEETIKNILFTTLEYFLTNDWVDNHLIILCASLHSLKAHLPTIFDENKSLYSLLPVILFSKPEDDGHVAAHFESIFSLLKEKALEDSGFSLKLCSEVQEWSLNKVLNGSINEKLAADKCVLVFNSFGKLPSNFFTFPASFWDAKISSCIPFFSNKLFIDQDFILGFLDLVASEPINVDMTDVGTQFVHIFHASLYTLYYVETTGCDGDALFNLTFAYLLIRIYLQNGIQSIIDVPIRDAGIFVESFECYFKGEVVKFMRDKDALTVLNELLIDDIDGKMPVLFKRFKNLSSAENTTSFSIFAAQGLTDFLIVVSNLLEMDEKHVDVVLGKLGLSSSKSPIFVSSILEGLKPLEVDSEIIQRIRFKAVNDLTGKLHSANEVSKSLLILNAATTQQITEKPLLPITRCRLFLENITNWCSESGIKSLELLPVCCFLRFMYYFLPTVFSLSGSYWNSIFDYIKYAMKMSVVDAPIVKSFELFALRLYNALSKNYEMNSDIKDCIVESNESMNYLLLKRFLFTHESTLRNSVTARMCNQYLVKLLENCPGKVVRSFQYQEFFPSLCNSNDLQMESVCMKFLREKLSHELKELTVYYMVESDYEPDVSLCPELLSLAIDFPGDPFVMVSKMEKYEHALRVYLLVWDLIFYHFEETTYNIKLSIINQLHAMDLLRPLLNTLVEILNLSYDRPINVDKYPKIDYNLMDYSSATDRIRCLAIHIYYQCLRHLSSSVRSYWSEVKNRAFTSTVESFTGYNVSPLLISASLDDVERSIESEDFQSVGDVNVKVNRNTREISFIYNVDEHKLEMAIKIPSVYPLQNVQVEGIERVGVNERQWRSWILASQSILSSQNGSITDALLVLKKNISMHFEGVEECAICYSVLSVERTLPNKRCGTCRHKFHASCLYKWFKSSNSSRCPLCRSSFTFV
Mass
184.4 kDa
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service
Make rkr1 using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)
Order Here