Protein expression services for upl-1 | E3 ubiquitin-protein ligase bre1
Description
E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation.
Family
Belongs to the BRE1 family.
Species
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Length
724 amino acids
Sequence
MPVATSPSAVPRPTTVKMEDRKRPAANADDVAPPSKRQAVNGTSKSKDDSNDSREEAWIEEYQKGAIYRQMLEYKRSKVDLEHRLQEAEKSAAFHDDHLRVIKYWLSQLTQELELIVEGSLKSIALKPVDSNWVSSLAFKDSKEFRQHLDDIKKPVILKVESLLNKLASSRGEVKPDVAQLEAQVKSLLANQKELAVKIDRLQAENATLSEQYDTATLKVIKAERKLDRVRSAQVQKLEQQALANSTTRQTTNDENGTSSIAENGDGAEYKTKYKEAIAVANKQKEQIESLLAEIKTLQEENASFKIKKEGISEEDYARTDVFKQFKAQNEDLIKRINNLEAVNKQFREDAEKLRAERTSYRATLEQEAQALTSDLEDQIQQKDQDLTRIRSARDELLAELAMRKASQEQEKTASAHLNELVEAMTDRVTQLESELERLRPTEDVAKAAPTDDLSTLSAEELREKFAKLERDYEAINKELPALEKSYRKAMGIAHKKVMDFTALEERVAILTAEKSKADQKYFAARKDMDIRIAEIRTLRGQNSKSSEIISQLKDVETQHRALITTLEKQIADLKQSNITIVTESKKLESLSSEATRRADSVKSQIENLQNLVKSKDTAGRELKEKAIDKEQEAEKLKVRLDKVSSERDKWKTKCQSNSTEEEEMLRNLVLCSVCRSNFKNTILKGCGHVFCNECVDNRLANRMRKCPSCNKAFDRSDAMPAHL
Mass
82.3 kDa
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service
Make upl-1 using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)
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