Multi-functional protein which regulates not only caspases and apoptosis, but also acts as an E3 ubiquitin-protein ligase mediating ubiquitination and subsequent proteasomal degradation of its target proteins. Acts as a direct caspase inhibitor. A key apoptotic suppressor in eggs. Acts as a positive regulator of Wnt signaling.

Belongs to the IAP family.

492 amino acids

MEPQLAEFVLKEEMTCQCPKMSDGAYDMDVDQNYFEEEVRLASFANFPSSYPVSAPALARAGFYYTGDGDRVKCFSCLAMVEGWQHGDTAIGKHRKISPNCKFINGFNNLRSDCILTQVPVMQNGFQNSAEDLAERSSSEIMADYLLRTGRVVDMSTPKYPRHMEMCSEEARLQTFQNWPAYSPLTPKELANAGLFYTGINDQVKCFCCGGKLMNWEPSDKAWTEHKKHFPECYFVLGRDVGNVATEANTHGGRRRGSELACPAMNDYNARLETFSSWSFPIDKETLAKAGFYSIGDGDATKCFHCGGVLNCWSATDDPWEEHAKAYPGCKFLIDEKGQHFINHAQLKRPILHKANSADASPALPKDSNLLKSPLVTDAQQMGFPLEEIKKVMGQKLKTTGKNYTCVEEFVSDLCAQKETVLEKPKEIEISLEEKLRQLEEEKICKVCMDRRISIVFIPCGHLVACAVCADVLDKCPICCTIVERRQKIFMS

55.3 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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