Protein expression services for hace1 | E3 ubiquitin-protein ligase HACE1
Description
E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division.
Species
Xenopus laevis
Length
944 amino acids
Sequence
MERAMEQLNRLTRSLRRARTVELPEDNETAVYTLMPMVMADQHRSVLELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKRGADPNYQDISGCTPLHLAARNGQKKCMSKLLEYNADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVTNVDVEDAMGQTALHVACQNGHKTTVLCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGGYGETCDILIQHHPRLFQTLIQMTQNEELRENMLRQVLEHLSQQSEVQYLKILTGLAEVATTNGHKLLSISSSYEAQMKSLLRIVRIFCHVFRIGPSSPNNGNDMGYNGNKTPRNQVFKVRNVSDVFRKINIKEMNLPKHTLIYQATSEQDPLELLWHSLDEWLVLIATELTKNKRDSSNIACILLKQSPLDQQDISLAHQSAIGESGNHDHLLASTRAGDLESCSAIGIQEPVADGQDVISMTANRLSAVIQAFYMCCSCQMPQGMTSPRFIEFVCKHDEVLKCFVTRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKERCEWFYEHLLAGQPDTDMVHRPVNENDILLVHRDSIFRSSCEVVFKSNCEKLKQGIAVRFHGEEGMGQGVVREWFDILSSEMINPDYALFTQSADGTTFQPNSNSSVNPDHLNYFRFAGEILGLALYHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGASILVTQENKAEYVQLVTELRMTRAIQPQINGFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVNDWMKNTEYTSGYERDDQVIQWFWEVVQELTQEERVLLLQFVTGSSRVPHGGFAYIMGGSGLQNFTIAAVAYTANLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA
Mass
106.6 kDa
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service
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