Required for normal myelination and for normal organization of the cytoplasm and the formation of Cajal bands in myelinating Schwann cells (PubMed:22764250). Required for normal PRX location at appositions between the abaxonal surface of the myelin sheath and the Schwann cell plasma membrane (PubMed:22764250). Possibly involved in membrane-cytoskeleton interactions of the central nervous system.

957 amino acids

MQPLVMQGCPYTLPRCHEWHAADRFHHSSSLRNTCPQPQVRAAVTIPAPPWDGAGDPCLSPKLLNGTVGATGPLEPSAMNLCWNEIKKKSHNLRARLEAFSDLSGKLQLPLREIIDWLSQKDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSKGPYISSVLESAQAFLSQHPFEELEESQSESKDTSPRQRIQNLSRFVWKQATVASELWEKLTARCVDQHRHIEHTLEHLLEIQGAMEELSSTLTQAEGVRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPVKDGVKLVNDLAHQLAISDVHLSMENSRALEQINIRWKQLQVSVAERLKQLQDAHRDFGPGSQHFLSTSVQVPWERAISPNKVPYYINHQAQTTCWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQASEHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKTGIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGALLHEAIQVPRQLGEVAAFGGSNVEPSVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSICRQCPIKGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFRSKQYFSKHPQRGYLPVQSVLESDCSETPASSPMLPHADTHSRIEHFASRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRHSSPITDREPAFGQQAPCSMATESKGELEKILAHLEDENRILQGELRRLKWQHEEAAEAPTLVEGSAEATPDHRNEELLAEARILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPSESDGNGSAGSSLASSPRQSEGSHPREKGQTTPDTEVADDVGSKSQDVSLCLEDIMEKLRHAFPSVRSSDVTANTLLAS

108.1 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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