Description
Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development (By similarity).
Family
Belongs to the dynactin subunit 2 family.
Sequence
MADPKYADLPGIARNEPDLYETSDLPEDDQAEFDAEELTSTSVEHIIVNPNAAYDKFKDKKVGTRCLDFSDRITKSKRTGYESGEYEILGEGLGIKETPQQKYQRLLHEVQELTQEVEKTQSTLKESATEEKLTPVALAKQVAALKQQLVSTHLEKLLGPDAAINLTDPDGALAKRLLTQLDAAKTRKDPEGKSSAKGPGPDNENLVTYELHCRPEQNKFSQAAKMAELEKRLGELEAAVRCDQDTQNPLTVGLQGSCLMDTVEILQAKVNLLDVASLDQVEARLQSVLGKMNEIAKHKATIEDADTESKVHQLYETVQKWDSMSITLPQVVQRLLTLKQLHEQAMQFGQLLTHLDTTQQMISNSLKDNTNALAMVQKAMKENLATVEDNFSSIDGRIKKLSK
Simulated SDS-PAGE

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service