Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein (By similarity).

737 amino acids

MWLLLLLLSGLSRLGGLSEPQTEGTREKLHVQVTVPEKIRSITSEGYETQVTYSLKIEGKTYILNLMQKAFLPPNFRVYSYDSTGIMRPLEQKFQNICYFQGYIEGYPNSMVIVSTCTGLRGVLQFGNVSYGIEPLESSSGFEHVIYQVEPKKGDTLLYAEKDMDLRDPQYKIRSIKPQRTVSHYLEIHIVVEKQMFEHIGADTAVVTQKIFQLIGLTNAIFAPFNLTVILSSLEFWMDENKISTTGDANKLLYRFLKWKQSYLVLRPHDMAFLLVYRDTTDYVGATYQGKMCDKNYAGGVALHPKAVTLESLAIILVQLLSLSMGVAYDDVNTCQCGVPICVMNPEALHSSGVRSFSNCSMEDFSKFIVSQSSHCLQNQPHLQPSYKMAVCGNGELEEGEVCDCGQEGCDDKPPPCCNPTTCQLSEGSTCSTGSCCDASCNLKAKGELCRPANQECDVTEYCNGTSEVCEEDFFVQDGHPCAEQKWICINGTCQSGAQQCRDLFGTDADYGTKECYSELNSKSDISGSCGITPTGYKDCAPNDRMCGKLICIYQSEDILKMRSAIVIYANISGQICISLEYPPGHKESKKMCVRDGTVCGSGKVCLNQECVEDTFLNYDCTPEKCNHHGVCNNKKHCHCEPTYLPPDCKNTEDTWPGGSVDSGNQQRAESIPARSYVASAYRSKSARWPFFLIIPFYVVILVLIGMLVKVYSQRKKWRMDDFSSEEQFESESESKD

82.3 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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