Probable disease resistance protein. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth. At the opposite of cultivar Kusabue, the cultivar Nipponbare doesn't recognize the effector avirulence protein AVR-Pik from M.oryzae.

Belongs to the disease resistance NB-LRR family.

1044 amino acids

MELAVGASEATMRSLLGKLGNLLAQEYSLVSGVRGDIQYINDELASMQAFLRDLSVVTEGHNHDNRRKDWMKQIRDVAYDVEDCIDDFAHRLPQDSISDAKCSFILTKMYELLTWWPRRDIASRIAELKVRAQQIADRRNRYGVNNPEHCDSSNSPRPRAHAAAQDIAEYQDTKPQIVSIKEPVGMKTVMENLEKWLTEPQPDKGRAVLSIVGFGGVGKTTIAMALYRKVSGKFDCQASVAVSQNYDEDEVLRSILNQVSKQEEAGGSTESSSRDENTREPQGSSSTSSREENTAESGTKRMLNKLKKALPLSLLGGNDDKTSVRQQETMGSLQLREELKRRLAEKRYILLIDDIWSAKTWNSIIIPFLPSENDKDSRIIVTTRFHAVGSTCSPRHKNDEATSSPGHGKDLLHKVDFLTGDKPLDLFNASIPDPMKRTDRDKKLSKICGGLPLAIVTMAGLVACNPNKANSDWSKLCESLFPYPVTTLNLDGVTRILDCCYNDLPADLKTCLLYLSIFPKGWKISRKRLARRWIAEGFATEKQGLTEEEVAEAYFNQLARRNLIRPVEHGSNGKVKAFQVHDMVLEYIMSKSIEENFITVVGGHWQMTAPSNKVRRLSLQSSGSKHGNSTKGLNLAQVRSLTVFGNLNHVPFHSFNYGIIQVLDLEGWKGLKERHVTEICQMLVLKYLSIRRTEIAKIPSKIEKLEYLETLDIRETYVEELPKSVGQLKRISSILGGNKNTRKGLRLPQEKRNKAMKNPSPQGKTKEPAEKGFLSQEKAKGTMKSLRVLSGIEIVDESAAVAASLHQLTGLRKLAIYKLKISEENDTFKELLSSIEYLGSCGLQTLAINDENSKFINSLYNMSAPPRYLVSLELSGKLKWLPEWITSITTLNKLTISITVLTTETLEILRNLPSLFSLTFAFSLSAAKQDQDTVKGILEDNKLATDGEIVIPAKEFKSLKLLRFFAPFVPKLSFPDKSAMPALEIIEMRFQEFEGLFGIEILENLREVHLKVSDGAEAITKFLVSDLKDNTEKPKVFVDGIVTA

117 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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