Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.

Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.

385 amino acids

MKYDVVVIGGRVAGSTAAYHAARLGLSVLLLERNPEIGTPVQCAGGVSDSFFKSTGLKPLPEFTCTRIRAAAVNGPLGARIVTENPVVRGYILERKSLDKYLALRAAEAGADVLTMSIAGDLIFREGSVSGVVFRGPDGVQEVECGMVIAADGVQSSIARKAGLETGFRPADLCSCVQYEVAGVDVDPETMEFYFGSRFAPSGYLWVFPKGEGRANVGLGIRRKSCSERGPLSYLNRFMEERGFKRIEFNAGAVPVCGPIERTFTDGLLVVGDAAGQVDPLTGGGIHLAAECAKIAGEVAAEAIESGRVDGRFLSRYEMRWRKKIGKNLERSLKFRKILDGLGDEELDALLRSLEGKDLSSISKISLLRILKDYPSMLRILRDIL

41.6 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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