Involved in the biosynthesis of ectoine ((S)-2-methyl-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid) which is a highly soluble organic osmolyte, called compatible solute, use to avoid excessive water efflux, plasmolysis, molecular crowding of the cytoplasm, and cessation of growth in high salinity environments. Catalyzes the conversion of L-2,4-diaminobutyrate (DABA) to L-aspartate beta-semialdehyde (ASA) by transamination with 2-oxoglutarate.

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

469 amino acids

MTTHKDLIDRDRKVTFHASTHLRDFAHGDAPGRVITGGKGIKIVDKDGREFIDGFAGLYCVNIGYGRSEVAEAIYQQALEMSYYHTYVGHSNEPQIALSEKILELAGPGMSKVYYGMSGSDANETQLKIVRYYNNVLGRPQKKKVISRMRGYHGSGIASGSLTGLKAFHDHFDLPIETIRHTEAPYYYHRAAEQEGMTEREFSKHCAAKLEEMILAEGPDTVAAFIGEPVLGTGGIVPPPEGYWDEIQAVLTKYDVLLIADEVVCGFGRTGSDFGSHHYGIKPDLITIAKGLTSAYQPLSGVIVGDRVWEVLEQGTGEYGPIGHGWTYSGHALGCAAGLANLAIIEREGLTANAAETGAYLQERMKAAFADHPVVGQVRGVGMMAALEFSVDPAARRHFDPSLKVGPRMSAAALEEDLIARAMPQGDILGFAPPLTTTREEVDEIVARTERAVNKVTDALTREGAIQAA

50.9 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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