Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion (By similarity).

993 amino acids

MTWLLFRTSGALAILMVLILVHGELRIETKGQHGEDETAIQGRRRYKREWVKFAKPCREREDNSRRNPIAKITSDFQATQKITYRISGMGIDQPPFGIFVVDKNTGEINITAIVDREETPSFQITCHALNVLGQDVEKPLILTVKILDVNDNAPVFSQSIFMGEIEENSASNSLVMILNATDADEPNHLNSKIAFKIVSQEPAGTPMFLLSRHTGEVRTLTNSLDREQVSSYRLVVSGADKDGEGLSTQCECSIKVKDVNDNFPMFKESQYSAHIKENTLTSELLRFQVIDWDEEFTDNWLAVYFFTSGNEGNWFEIQTDPRTNEGILKVVKALDYEQLQSVQFSIAVKNKAEFHQSVISQYQVKSTPVTIQVVNVKEGIAFHPASKTFTVRKGISSKKLVNYVLGTYQAIDEDTNKAASYVKYVMGRNDGGLLFIDPKTAQIKFVRNIDRDSTFIVNKTITAEVLAIDENTGKTATGTIYVEVPGFNENCPTVVLEKKAICSSLRSVVVSARVPDNKYTGPYTFSLEEQSLKLPVVWSITTLNATSALLNAQQQLSPGEYTISLTVTDSQDRQCETPESLTLEVCQCDNRDICRSSNGNKDYERLDGKRPSGRLGSAAIGLLLLGLLLLLLAPLLLLTCDYGVGPIGGVTGGFIPVPDGSEGTIHQWGIEGAQPEDKEITNICVPPITTSGADFMENSEVCTNTYAGGTVVEGASGMELTTKLGAATGSGAAAGFGATAGFGAATGLGIGSAGQSGTMRTRHSTGGTNKDYGEGAISMNFLDSYFSQKAFACAEEDDVQEANDCLLIYDNEGMGAPSSPVGSLGCCSFIADELDDSFLDSLGPKFKKLAEISLGIDDEAKQSQPLSKASLSGMESCGYSLEVQQPESVRGQTLLGSQGASALSASSSVLQSATSIPNPVQHGSYMVTETYSASGSLVQPTTTVLEPLLTQNVTVTERVICPISNVSGNLQTPMELRGSRNMICTEDPCSRLI

107.6 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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