Catalyzes the hydrolysis of the amide bond in N-(4-oxoglutarate)-L-cysteinylglycine (deaminated glutathione), a metabolite repair reaction to dispose of the harmful deaminated glutathione. Plays a role in cell growth and apoptosis. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells. It is also a negative regulator of primary T-cells.

Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

328 amino acids

MLGFIIRPPHQLLSLLSCPGLRIPRFSVLCAPPRLRTMAASSSFSELPLVAVCQVTSTPDKEQNFKTCAELIREAARLGACLAFLPEAFDFIARDPEETRRLSEPLSGNLLEEYTQLARECGLWLSLGGFHERGQDWEQTQKIYNCHVIMNNMGSVVATYRKTHLCDVEIPGQGPMRESNSTIPGPSLESPISTPAGKIGLAICYDMRFPELSLALVQAGAEILTYPSAFGSVTGPAHWEVLLRARAIETQCYVVAAAQCGRHHEKRASYGHSMVVDPWGTVVARCSEGPGLCLARIDLNYLQQLRKQLPVFQHRRPDLYGNLGHPLS

36.2 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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