Probable helicase, member of the UBC2/RAD6 epistasis group. Functions with DNA repair protein uvs-2/rad18 in error-free postreplication DNA repair. Involved in the maintenance of wild-type rates of instability of simple repetitive sequences such as poly(GT) repeats. Seems to be involved in maintaining a balance which acts in favor of error-prone non-homologous joining during DNA double-strand breaks repairs (By similarity).

Belongs to the SNF2/RAD54 helicase family.

1228 amino acids

MDRHDTMDFTNEPLSKKRRFLGDQGDSDHVAGGPSSSPQFSAPPSSPPRKKLLQDPNSEVQPRVSKDADHNDDDDDDDDDDDEERPRFFTDDGTLTPHATKICAPWLNDMPKPDPRKGYLLKDVDTPIATPRDVAPPVVESPQLAFDKDTFEAFVGEKVASDILHVISKNCGNNIERAVNMYLDGTWKKLHRAPPVRVNSHSPLVVGGQSPKKSSTSQARSRSHAQAQPQPQSNTPTKVLPSMPDARYVGAFGVEGWATRSGTGLLRHGDSVKIERQKIQPPTVARKGQTKPGTPQSIPRVSAAAAKRVDVIVRFNDASGRELGRLAKDTANWVSTLIDQNICRFEGICVYAPERLRTNETVFLQLKCYMLRSAFLGRTLQLADNRAAGFHEKDETTEEKDLRLRQVALVRLFQEINIVPSRGNAAAAKDARKDLLEAADSAEKKAMDKAKAGDHNTNGLASPPEEAEEGQELEQDQLDALYKKAQSFDFSTPEAEPANTFAMTLRPYQKQSLYWMLAKEKNQRTEDRETSMHPLWEEYVWPTKDHDDKDLPVVPDQPCFYVNPYSGDLSLDFPKQEQHCLGGILADEMGLGKTIQMLSLIHSHRSEVAIKAREAGPTSVNNLPRLPTVSGQKTTIDAPCTTLVVAPMSLLAQWQSEAENASKEGTFKTMMYYGAEKNVDLVTMCCEANAANAPDVIITSYGVVLSEFTQLATKNGDRLSSRGLFSLNFFRVILDEAHNIKNRQAKTSRACYEIAAEHRWVLTGTPIVNRLEDLFSLVRFLRVEPWNNFSFWRTFITVPFESKNFVRALDVVQTVLEPLVMRRTKDMKTPDGQFLVPLPPKHIEIVDIELSEPERAVYDYVFNRAKRTLFDNMQAGTVMKAFTSIFAQILRLRQSCCHPVLVRNQEILADEEEANMAADVAAGLADDMDLQTLIERFTATTDDASKTNNNFGAHVLRQIRDEAVNECPICAEEPMIDQAVTGCWHSACKKCLLDYIKHQTDRNEVPRCFQCREHINIRDIFEVIRHDDDLETSSTPGASPEPRISLQRVGANDSSAKIVALISHLRTLRQEHPKMKSLVISQFTSFLSLISSALTRHKISFLRLDGSMSQKARAAVLTEFQSTNKFCVLLLSLKAGGVGLNLTSAKRVYMMDPWWSFAVEAQAIDRVHRMGQEDEVRVYRFIVKQSVEMRMLRVQERKKFIATSLGMMSDEEKKMQRIEDIKELLSSD

137.9 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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