Description
Involved in DNA double-strand break repair (DSBR). The RAD50/MRE11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific exonuclease activity. RAD50 provides ATP-dependent control of MRE11 by unwinding and/or repositioning DNA ends into the MRE11 active site (By similarity).
Family
Belongs to the SMC family. RAD50 subfamily.
Species
Encephalitozoon cuniculi (strain GB-M1)
Sequence
MASIKKLMIRGVRSFSHKESNTLEFYSPLTLIVGANGTGKTTIIESLKYATTGSLPPNSRGGAFIHDPSVAGLAEVQGQVKLLFTNVHGETMICSRTIQLAQRRDRREQKTLESVIWAERDGEGVSGRSGDVDAEMPQHFGVSGSILESIIFCHQEESTWPLGEPVVVKKKLDDIFASAKYGKALDSLKSSRKECSSDVKMKMQELEFLRKMKERKESLELRIRSGCMSIEKNEIRVEACDNEIGRCERVIEEIDLELKGNEEAEKRAHLLRGEHRELMEFIDGFREKKLPLEDATDIMSGKSLQEAEEEYERMKMDAEESEMRFKDLSEERSRYIRSKAELDGVFSEISVKSSFLDEARRQKMEALKSLESELKVKKDFRETALEVFGKVEDDIKQRKECIHRLEEEALRLKKEDRDRTVALSEKKRIVDEYSGLESDGSIDVSVSYEDEVGRLRAEISRDREMEALEERLGDYQRRLNDAYSIAERNFAMNQMRGRKREIEGMLNGVNVSELKSKLERQKAKLREKESRAKEIEREMSLRKARAIERSKENDRIRRELRTKSMELGSMGQRSRMAIFEELGIPMLRNGSRCSVERAKEVVRSNEGFFARDDMGFGVEMLDLESLYDGEEVLQRSGASDGIWRERIYREMLEDGCRSHECPVCNKPLSKEEEVEFKRKLEAGIERALDGKENALGSWNDRERIAGEIEALNKEIAGRNKIREEMAELILRYEEVEDVSGEEALDEMELDMLDEAEGIKKTEFLIGLVEELFLIDGKLRGSEEGESVQELRSMVDGIRKIYEEKKEEVRRKKERIEYLCRKQEVIRAEREIREKINFREEAKEAMQRIERSSARIRASDVEEEIRRKKSKLDRILERFARKRVELEMSMEAFYQKEREEACLAKEIEELNSKVRKLLQAEFLDEAKDEVKFDDARSDLLERKNKVLEIGQKIRRMYEMRSLAEESMKYYNRERRVREIERELSETDFEYLAALKEKRRLLEEKKAKLSSQKSLLLGECKQIALGVKSYKQELLKDHGRTVENYNKCFIEVKALELSCMDLDKCIQALDKAIVDFHTSKLEEVNATLKDLWTNTYRGDDVDWIKIKTESSGQRTYNYKVVFVKGGVELDMRGRSSAGQKMIASILIRLALADSFASSCSVLALDEPTTNLDRDNIESLAFTLSRVISRHRRDADFQLIVITHDEDFVQLLSRGGPEYFYRLSRSESGDSMIVRHSIYGTREMGPNKVY
Simulated SDS-PAGE

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service