This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

Belongs to the DNA mismatch repair MutS family.

873 amino acids

MQTTDFNTKASSPKSTAEHTPLMKQFFAAKSDYPDLLLFFRMGDFYELFYDDARKAARLLDITLTQRGSSGGAPIPMAGVPVHAYEGYLARLVALGESVAICEQIGDPALAKGLVERKVVRIVTPGTVTDEALLDERRDTLLMAISRSKQGYGLAWADLAGGRFLVNEVDTVDALEAEIARLEPAELLVPDEDHWPEFLRGRIGVRRRPPWLFDADSGRRQLLAFFKLHDLSGFGIDDKPSATAAAGALLGYVEETQKQRLPHLTSIATEVASEAISMNAATRRHLELDTRVDGDTRNTLLGVLDSTVTPMGGRLLRRWLHRPLRLRDVLVQRHHAVGNLIDAGADADLREAFRALGDLERILTRVALRSARPRDFSTLRDGLALLPKVRTILAPLDSPRLQTLHAELGEHDATAHLLISAVAETPPLKLSDGGVIASGYDAELDELRRLSTNADQFLIDLEQRERASSGIATLKVGYNRVHGYYIEISKGQAEKAPLHYSRRQTLTNAERYITEELKTFEDKVLSARERSLSREKLLYEGLLDTLGTELEGLKRCAGALSELDVLAGFAERAQALDWSQPELDSAPCLRIERGRHPVVEAVRDHPFEPNDLDLHSDRRMLVITGPNMGGKSTYMRQNALIVLLAHIGSYVPASRAVIGPIDRILTRIGAGDDLARGQSTFMVEMAETSYILHHATPQSLVLMDEIGRGTSTYDGLALADAVARHLAHTNRCYTLFATHYFELTALADESHDGGASGIANVHLDAVEHGERLVFMHAVKDGPANRSFGLQVAALAGLPKAAVTQARRRLVELEQRGGESHSAQMAPTALDAPQQFGLFTAPSSAAQEALQALDPDELTPKQALEALYRLKALL

95.8 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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