Protein expression services for MSH6 | DNA mismatch repair protein Msh6
Description
Component of the post-replicative DNA mismatch repair system (MMR). Involved in B cell growth by positively regulating B cell proliferation and controlling replication efficiency. Controls cell cycle to prevent re-replication and defects in DNA damage-induced G2 checkpoint. Doesn't seem to counteract or control the immunoglobulin gene conversion (Ig GC) and to contribute to guanine/uracil mismatch repair.
Family
Belongs to the DNA mismatch repair MutS family.
Species
Gallus gallus
Length
1337 amino acids
Sequence
MMSASNLSVIHEVLLVLLNHQRINLPYENLEASLSRMLFLSSFVQEVVQVPIPCNVSANRSVSGVYSPGDLVWAKMEGYPWWPCLIYNHPTEGTIVRGKGSSARIHVQFFDVSPTRGWVSIKYLRPYKGSSDREVLKGGMFYSMKPEIKKAMELADDAMSKDKTKRLELAVCSEPSDTEEAEEEEMEQMSGSASGDSDDSNSEEDVKGNKRVPNRGSAIKAKRRRVLDSDSDRDGSDVEFKPDVKEASSEEASSGVDENEATDVETDEESIEESPIKVPSKRKRGNVSKPSKRSSLENEHSEAPKRAAPVSLEAKSKLTLFAAPENFESQANACSGGTNGFAAWEHEKLEWLQEGKKKDAHRRRQNHPDYDPCTLYVPEDYLNKCTPGMRRWWQLKSQNFDAVICYKVGKFYELYHMDAVTGVNELGLIFMKGSWAHSGFPETAFGRFSAILVQKGYKIARVEQTETPEMMEARCKATAHTTKFDKVVRREICRIITKGTQTYSIIDCDPTENHNKYLLCVKEKEDSSGQRVYGVCFVDTSVGKFYVGQFSDDRHCSRFRTLVAHYTPVQVLFEKGNLTVDTQKILKGSLISCIQEGLISGSQFWSASKTLKVLLEEEYFKENQNTESGCVLPSVIKSLTSESDSLGLTPGENSELALSALGGIVFYLKKCLIDQELLSLANFEKYIPVDADNAKTVSSSNFFARTDRRMVLDGVTLMNLEVLQNGTNGTTEGTLLERIDSCCTPFGKRLLKQWLCAPLCNPTSINDRLDAVEDLLAVPAKLTEITEHLKKLPDLERLLSKIHSIGSPLKSQNHPDSRAIFYEEIKYSKKKIADFLSALEGFKVMNEIVDAMEEVASDFKSQVLKQLVTRKAKHPDGRFPDLSAELKRWDTAFDHNQARKTGVITPKAGFDPDYDKALQDIKTVEEDFRTYLDKQRKLLGLKSVLYWGTGKNRYQMEIPETATSRNLPEEYELKSTRKGYKRYWTKEIEKMLAELINAEERRDAALKDCMRRLFYNFDKNSQDWQTAVQCIAVLDVLMSLANYSQDGDGPLCRPVILLPVDSAPPFLELKNARHPCITKTFFGDDFIPNDIVIGSKDEDGGSEASCVLVTGPNMGGKSTLMRQAGLLVIMAQLGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFVELSETSSILQHATEHSLVLVDELGRGTATFDGTAIASAVVRELAENIKCRTLFSTHYHSLVEDYSGSAAVRLGHMACMVENESEDPSQETITFLYKFIEGACPKSYGFNAARLADIPEEIIQKGHRKAKEFEKKTMSLRIFRFLCRVVDGVTHDANAVGKLTTMLSHL
Mass
149.9 kDa
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)Safety
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Protein synthesis service
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