Forms a complex with the serine/threonine kinase MEC1 which activates checkpoint signaling upon genotoxic stresses. The MEC1-LCD1 complex is recruited to DNA lesions in order to initiates the DNA repair by homologous recombination. Required for cell growth and meiotic recombination (By similarity).

664 amino acids

MADLWDDNDDDDDILELVNRPPMSQMAVPIKPPESQAEQLMKAKGEVGVLRQKLSMLEKTLREHDDNQKKLESSLKSSHEEEVTKLKIELERLEDERKFMLLEQKHLFTPRNSSKSETTHETETAEPSPIENKRRRMEPVKEYVTLTQNFKVDDGSLFYDHLLNFKLLGSEHTVLEMLDHICTYKTDLILSPEHKIIKARLPLGPPIRSLIFKWKSIYTLDQLVDKTLEILAIAIKSVSVLPENKLAIPFLISLMHCTINFRHSATSVSSLKDVFQFITDFIISDPKFLKQPLHESPLDLDVSPDVFQYSMLDQLCMTYSFDVLETCIVILLNCNTRAQEIVLNDATIAENLIKCCNFTLSISYKPIMPIIVNVTEILLGIVELDGAENVWKGKWAVLFSKLIQNWERSLTFDSVSLNFAGLNRCCGDNSNHSMIDNIISLEEVRYLPMIIENEFEPLTFTALDNLEYWSIQIQINITLIMHKLLHRYRSTLCSLEFLQKTFSLFSSHQELLLTVFLDRDHISDIKRQELLSVLLKLIYFCWVSISDEYKRALRLDELTICLWRIVYGWPESTDELSTEWAALINPLKALALEEEKKYFDDAYDEDNLPAFMHSEELDIKRESAVSKFNNNSSWPLRDMAKYILESITTMDEADSLYVAMVSET

76.9 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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