Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

Belongs to the cytochrome b family.

393 amino acids

MRLLKTHPILGLANSYLIDSPQPSNISYMWNFGSLLGVCLIIQILTGVFLAMHYTPSVDLAFISVEHIMRDVNYGWLIRYLHANTASFFFIFVYLHIGRGLYYGSYKSPRTLLWSIGVIILVLMMAIAFLGYVLPYGQMSLWGATVITNLLSAIPWIGQDFVEFVWGGFSVNNATLNRFFSLHYLLPFVLAALAAMHLLALHEHGSSNPLGVSGNTDRLPFHPYFTFKDLVTIFVFLLALSLFVFYMPNAMGHSDNYIPANPMQTPASIVPEWYLLPFYAILRSIPSKLIGVLAMFMSLLILLGMPILDTSRIRGSQFRPLMRFSFWTFVACFFILMFIGSQHVESPYVEIGAAATAYYFAWFLVVVPAIGIIENTLMDIALTEETSSFHRVV

44.4 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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