Responsible for the hydrolysis of cyanuric acid, an intermediate formed during catabolism of s-triazine based compounds in herbicides such as atrazine and polymers such as melamine. Catalyzes the hydrolytic opening of the s-triazine ring of cyanuric acid (2,4,6-trihydroxy-s-triazine) to yield carbon dioxide and carboxybiuret, which spontaneously decarboxylates to biuret.

Belongs to the cyclic amide hydrolase (CyAH) family.

369 amino acids

MPRRAEILRLPMAAPDDVSAIAASLRDGRLDPGDVVAVFAKTEGNGCVNDFTRPLAVQALRGLFGPLIGEAALGRIAMVMSGGTEGGLSPHWLVIAAREAAGPGPALAVGQARTPPLAAEDLGRRAQVEMVAAGVRAAMREAGLDAGQVHYVQVKCPLLTSERIGAALARGAAPATRDTLKSMGLSRAAAALGAALALGEVPAAAIGETVAETDPGRHARRCGASAGVELLDHEVVVMGMSPDWTGPLVIDHAVMADAIDLRPVAACLGRLGLLGPDGFVDEAGRARLAALLAKAEASADGAIRGRRHTMLTDSDIAPTRHARGFVAGALAGLVGATDLFVSGGAEFQGPDGGGPVAVIARRSGAAGPA

37.2 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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