Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

Belongs to the CobB/CobQ family. CobQ subfamily.

484 amino acids

MTRKIMLQGTGSDVGKSVLVAGLCRLASNHGLSVKPFKPQNMSNNAAVADDGGEIGRAQWLQALAARVPSSVHMNPVLLKPQTDVGSQVVVQGRVAGQAKGKEYQALKPSLLGSVMESFEQVSAGADLVIVEGAGSPAEINLRAGDIANMGFATRADVPVVLVGDIDRGGVIASLVGTHAILPGDDRRMVTGYLINKFRGDVTLFDDGIASVRQFTGWPCFGVVPWLKSAGRLPAEDSVVLERLTRGGGKALKVAVPVLSRIANFDDLDPLAAEPDVDIVFVRPGTPLPDDAGLIVIPGSKSTIADLDDFRRQGWDRDLDRHMRRGGRVVGICGGYQMLGSRVADPLGIEGGKREIEGLGLLSVETEMAPEKTVRNSRAWSREYDVALEGYEIHLGKTTGADCSRAPVEIDGRPDGAMSADGRVMGTYLHGLFGSDAYRSALLKSFGIEGGGGNYRRSVDAALDEIALELETVLDRAWLGTLLG

51.3 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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