Protein expression services for CHAF1A | Chromatin assembly factor 1 subunit A
Description
Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci.
Family
Belongs to the CHAF1A family.
Species
Bos taurus
Length
964 amino acids
Sequence
MLEEPECGAPGARGEAAAMDCKDRPAFPVKKLIQARLPFKRLNLVPKEKIDDGLDDTGGSRAGPVQTQLHNLETSLDHLENCHMGSDIDFRPKLVNGKGPLDNFLRSQVETSIGQAVVIIDLTEDSSNPPDNMVGHNKLNSAASSAQKNINGVPDKAGDDRGLPKARQKDELASPEEALSEVPCKTEAGGADSGGADRRGLTQRGSPQNCPKLTGDLSMWSEKDRDGWSEAGGILFKGKMPVVVLQDILALRPPARSPPATPPSQAVPSESETPESSPEEDLALSHSSLSSSSPTSSPEGQSVPTKLHTGPSPFPASTPVCRITKKLVRGSAEKNKMKLQRDKERLRRQLKLRAEKEEKEKLREEAKRAKEEARKKREEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITRFFQKPKTPQAPKTLAGSCGKFAPFEIKEHMVLAPRCRTAFDQDLCDQLDQLLQQQSSEFSFLQDLKSRRPLRSGPTVVSNRNTDLSNSDVVIVESSKVDGVPERRKFGRMKLLQFSENHRPAYWGTWNKKTTVIRPRDPWAQDRDLLDYEVDSDEEWEEEEPGESLSHSEGDDDDDVGEDEDEDDGFFVPHGYLSEDEGVTEECADPENHKVRQKLKAKEWDEFLAKGKRFRILQPVKIGCIWAADKDGGADLKVLQQFTACLLETVPPEEEQTPKASKREKRDQQILAQLLPLLHGNVNGSKVIIREFQECCRRGLLSRDAGSPEDSAASPPSPGPARPQTPTASEDVAVPSKARLKRIISENSVYEKRPDFRMCWYVHPQVLKSFAQEHLPVPCQWSYVTAVPSATREDSGSVPAPGPGQGMPVSLKRKSAGSMCITQFMKKRRHDGQVGTGDLDDFQADTEEEDDDEGDCVIMDISDVGDIQAPCGTTSGAGGSVGMDTSESFVSPSSLRLS
Mass
107.3 kDa
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)Safety
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Protein synthesis service
Make CHAF1A using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)
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