Description
Plays a role in host liquefaction to facilitate horizontal transmission of the virus by hydrolyzing beta-chitin and by regulating the cysteine protease VCATH. Localized in the host reticulum endoplasmic via its KDEL motif, interacts with and thus prevents VCATH secretion before host cell lysis occurs.
Family
Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.
Species
Autographa californica nuclear polyhedrosis virus
Sequence
MLYKLLNVLWLVAVSNAIPGTPVIDWADRNYALVEINYEATAYENLIKPKEQVDVQVSWNVWNGDIGDIAYVLFDEQQVWKGDAESKRATIKVLVSGQFNMRVKLCNEDGCSVSDPVLVKVADTDGGHLAPLEYTWLENNKPGRREDKIVAAYFVEWGVYGRNFPVDKVPLPNLSHLLYGFIPICGGDGINDALKTIPGSFESLQRSCKGREDFKVAIHDPWAAVQKPQKGVSAWNEPYKGNFGQLMAAKLANPHLKILPSIGGWTLSDPFYFMHDVEKRNVFVDSVKEFLQVWKFFDGVDIDWEFPGGKGANPSLGDADGDAKTYILLLEELRAMLDDLEAQTGRVYELTSAISAGYDKIAVVNYAEAQKSLGKIFLMSYDFKGAWSNTDLGYQTTVYAPSWNSEELYTTHYAVDALLKQGVDPNKIIVGVAMYGRGWTGVTNYTNDNYFSGTGNGPGSGTWEDGVVDYRQIQKDLNNYVYTFDSAAQASYVFDKSKGDLISFDSVDSVLGKVKYVDRNKLGGLFAWEIDADNGDLLNAINAQFKPKDEL
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service