Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones. Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin (By similarity).

Belongs to the chalcone isomerase family.

235 amino acids

MATPSSATSLNVENIVFPSSVKPPGDTNTLFLGGAGVRGMEIQGNFVKFTGIGVYLEDKAIPLLAGKWKGKTAEELVNSVEFFRDIVTGPFKKFTQVTMILPLTGKQYSEKVSEMCVGVWKAHGTYTDADGATIDKFLEVFKDENFPPGASILFTTSPDGSLTISFSKDGMIPEAANIVLENEKLAQAVIESVIGKNGVSPATKQSLASRLADLMNHFDEKATTDAEPNLSKNGL

25.2 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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