Description
Involved in programmed cell death/apoptosis. Acts by recruiting ced-6 to phagosomes which enables actin-dependent cytoskeletal reorganization and subsequent engulfment of the apoptotic cell corpse. Has a role in the association of ppk-3 and rab-7 with the phagosomal surface which is necessary for the incorporation of lysosomes to phagosomes during phagosome maturation. Activates the expression of unfolded protein response genes, which are involved in the immune response to live bacteria (By similarity).
Species
Caenorhabditis briggsae
Sequence
MRLLLLVGVLLAATWQVGYTRAPTFPDKSKSAADAINEPKGEHVCTVKTIVDDYELRKVIHQVVYNDTEQCLNPLTGFQCVVEKRGQKASYQRQLVQKEKYIKQCCEGYYQTKDNQCQPDCNPPCKKGKCVEPGKCECDPGFGGKICSSSCSIGTWGLGCSKKCDCENGANCDPELGDCICPSGFQGKRCEEECPIDKWGPNCVKSCPCQNGGKCNHEGKCVCTDGWGGEYCLNKCEEGKFGADCKFECTCQNGATCDNTNGKCLCKSGFHGALCEKPCSEGFFGAGCTQKCQCLNNQDCDSETGECKCIGWTGKQCDIGCARGRFGLQCKQKCTCPGLEFQDSNASCDAKTGECQCESGYKGANCDERKCSADTYGADCSKQCSCVMSNTVMCAPNTGFCRCKPGFYGDNCELACSKDSYGPNCEKQAMCDWTHASEADPANGKCVCKSGRSGANCSQPCPIDFYGPNCALQCECNGRGIGCHGFDGKCNCAPGYTGHRCEHHCPALTFGANCEKRCQCPAGVGCNPITGECECPAGRQGLKCDISCPEGSYGPECKLHCKCVNGKCDPETGECSCEPGFGGADCSTSCPKGKYGDACELSCDCSDSYCSRQTGKCICPLGKKGTLCDQPCEANTYGPQCQLTTTPSQCASTDPRNGVCLTCPPGSSGHQCEQNCPQGTYGTDCASKCACADGGHGCDPTTGECICEPGYHGATCSEKCPDGKFGYACAQNCPKCAAGSSCDHISGQCVCPAGLEGATCTRPCGVGFWGNGCRQVCRCTSEFKQCNAQTGECSCPAGFQGDRCDKPCEDGYYGPDCIKKCKCQGTATASCNRVTGVCICHPGFTGEFCHALCPESTFGLRCSKECPKDGCGDGYECDAAIGCCHVDQMSCGKAKQEFEALNGGRAKSSGATWLLILFIIGLCGVLGLAALFYRNKYQKEKDPDMPTVSFHKSPNAEDNREFQNPLYNRQSVFPDSGAFSGSSEGGVGAAPDGLLTLEEEDLEDKKIHGGGASRNMRNHDYASLDEVAGGEGGPATSSSSGVQNRRGQNSGDVRRPLLNSEDVDDDDEDEDFEEIPHENRNSTQKLSLERNSKFSEKNFKKKFLSENPYAHIPSPDPNIQNSTNSRRAQENLYT
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service