Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH. Probably is the signaling protease that mediates the first proteolytic cleavage within the signaling protease box of pacC (By similarity).

Belongs to the peptidase C2 family. PalB/RIM13 subfamily.

854 amino acids

MSRPNASAQKSFITQALKAERDVSSATSQRQALEAAIDAAEHYMKALNLASVQKDKHALDAKCKEWLTRAEKIKESKDWQAAARFHDKTVPEPRLPVSTRKLTTREEIILLEGAKLNGFIFPPWSTSPGSDEFKREDGESPFTDKPDLHLSYPQRKVFDGWKRPSELLAKDTEDVYTKVVPVMSVPGKTDLVQDMLTDCSVVASLCATTSMLERGQCTHFLPMIYPSRGSSQPSPSGKYIFRFYFNGCFRKVIIDDRLPSSKTSRSLHVIDRKNPNFLWPALVEKAYLKLRGGYDFPGSNSGTDLWVLTGWIPEQVFLHNDDVTGDQLWKRLYRSFHQGDVLLTIGTGELTEREQRELGLVSEHDYAILDMKESKGRRQLLVKNPWAGADTAPGDNGSLSASQDLPHNPPSFEPGTFWMDCEKLLQHFENLYLNWNPEIFKYREDVHFTWDLNNGRGVAGCFVNNPQFAVSTENGGIVWLLLGKHFRTTGQPERPLDEYQANEESAFISIYVFNADGKRVSLSDGALHRGPYVDSPNTLMRLEMPPRTTYTVVVSEQSLPSLNQNFTLSAFSTCPVRMAKAQDKYMCVRKIQGSWTPSTAGGNAESSRYPLNPQFRLEIENDTDVSLLLECPNTELATHVKLFWSNGNRVSRVRSRDIIADSGDYRRGGSLVEKKALEPGSYTIVCSTFAPDQLGRFTLWVSSLVPCKTSPLPPEAAGRRTVISDIGVLPPGRDRMLASLQVPRLTRIKLITRSRQSIIGSHPVGPSPVLMTVELGQGPYKQILATSEDGTHSDAVSGVRVEDFDLQPGLEESGGIWIVIERIGGPGGQVEDHFEVEALAEERVEIGEWILEDA

95.5 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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