Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes (By similarity). The CSN complex seems to link protein degradation to sexual development. May be required for sporulation only at elevated temperatures.

Belongs to the CSN7/EIF3M family. CSN7 subfamily.

327 amino acids

MDQVHHRALDALQSFIALTDSSSATSPRYIASIITNATSSPHTYVFAELLERPAVQALRSPDTPAEFQSYLTLLEIFAWGTWQDYQQTPNLPPLSEEQARKLRLLTLLSLASTIKPLTYEALMTSLSLSAPSELESLVTTAIYSSLITGRLSPATNPPTVNVTSVAPLRDVKPSSLPTMISTLTAWEARCGSVISDIETEIAKIRADSAQRRQKEHARAVAIEKTLEKWNAEGGEQLQGGNPGQGQGQGQGGLGKNAGWKPRDLSTAMFERGFFGGGSNKREFDDDGYFDGGSSDFDQHGSGMDIDEGAGARASGARHSKRFLGKKS

35.3 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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