Description
Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes (By similarity). The CSN complex is involved in the regulation of the circadian clock through its control of the stability of the SCF(FWD1) complex.
Family
Belongs to the peptidase M67A family. CSN6 subfamily.
Species
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Sequence
MAAATVNPLMSTLKSDSSLQVALHPLPILEISDYITRSYLRGYKGAIVGALIGQQNGRQITIEHSFSVKTEHTGQNYKVDSEWFTARLDQMKAVHKDRALDFVGWYTLVPKSGPTDAHLPIHSYFYSQNESAVLLGFHIHEILNPVAGDPLPLTIYESNLEIVDGTEASTVEVEGEDREMKDVTAEPSRSIKFRELPYTTETGEAEMIALEFVREGGSANVTTTATNITATEDEGSDKPLMKKVVDTNKGSKRRAVSSDDAAAEAPTTSSAAKGTATDKNRDANLTKAELDYMSALQAKYNAVQMMKKRLDTVISYLQRLPPDYLSSGDASSQQQQQQQQQQQTEGLDQPQYTVPSNKILRQIQALVTNVQLVMSNSTSGQGQGQGERDTDLGALEKELLKETNDVKLVELIADLMSSVKDMKEVGKKFHVVETAKNSKRREQASHGGGERFNPHHPYPGGGGGSSMMREHAGLVGEGSASGSGGSGPAGDLARFDH
Simulated SDS-PAGE

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service