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Protein expression services for jmjc-1 | Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66

Description
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code (By similarity).
Family
Belongs to the ROX family. NO66 subfamily.
Species
Caenorhabditis briggsae
Length
776 amino acids
Sequence
MGKKNKSNGGGNTNNTPTKTPSKPPVKFNDKWASIENGEAKSASVSHYKEPSKEPKFVHPAKLAKEKKIFDGLDIPERVLAHGKVVEQNGGKKRRHREISPKMEAKKPKVESKSKDGVAAKKAHKHFTVSSEVVQSTYFFEEPDNGNEVTLVSNGKETTIEKTVILDEEVEDEEIDEEEFEDEEEVEDEEGMDEDETEIDESEMIVDPKDIERCIEFEDVDDEDEMEDEEEFEDEEEVEDEEVDDEEEEEVADEERGEEQEDEQEEEEEVSDEESVVSEMDADSDDEGFIAGKDREAHVISKDKAARTFAAKPVDFDAFPFNDQDSVVTASRAFGFMVSPCDVQTFFDKFYQSNVLVVHRKTPAYYGNLFSTTRFSELLEKHYLEYNMNINIAQYKDGIRTTLNGKGRVYPQIVKQHLHNLCSVQLVNPQTFDDRIWYLCEILQEQFGCFVGANTYLTPAGSSGFAPHWDEIDAFLLQVEGRKYWRVWAPESAEEELPLESSGNFTEDDMKGKEPVFEGWIEQGDMIYIPRGYTHQARTDKKVHSLHVTVSTGRQWSFANLMEKVIPEAVGALTEERHKLRRGLPIGLFDMGGVVDLDYSQEEHFTEKFKIVVDRHMSRLRNLVADHLLDSSVDSMTKEFMKQALPPILTDKEKKRSVIGLSTNLLGDDLIDFCANTKVKFIRKHTQRLLMESEDSCFISHRMNNSRLFEGRPETLVDFPSTGIDTYRVLWNAYPEWRTLDEIFSCRETKSNTRKEKLAAIQILFQMGVLLVKNPK
Mass
89 kDa
Simulated SDS-PAGE
Western blot of jmjc-1 recombinant protein(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service
Make jmjc-1 using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)

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