Description
Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity).
Family
In the C-terminal section; belongs to the thymidylate synthase family.
Species
Paramecium tetraurelia
Sequence
MTTNKTFSMVLAMTLNGGIGYQNRLPWKLKEDLQRFKKITTGGIVIMGRKTFESMNSKPLPNRVNVVISKNMKSSNEVQVFPRIEDALQFYNTSHQKLYLIGGKRIFEEGLATDKCSDVHLTRIGVETKCDVYLNKNIFSTFQVNKTSQTKSENGINYDYQHLINKNSHEQSYIDEEHQENQYLDMITKIMKEGVSKDDRTGVGTMSIFGQTMRFNLAQSFPLLTTKKVFFRGVVEELLWFLRGNTNGKLLLDKGVKIWEGNGTREYLDTIGLQHRQEHDLGPVYGFQWRHFGAKYKDCQTDYSNQGVDQVKEIIQLLKNNPDSRRIILSAWNPIDLKQMALPPCHVMSQFFVANGKLSCMMYQRSCDFGLGIPFNIASYALLTYMLAKECNLNLGEFVHVLGDTHIYSNHVEALKKQIERVPYPFPLLKIKGNKSLFDYTYEDFELVGYNAHDKIEMKMAV
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service