Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues.

Belongs to the glycosyl hydrolase 20 family.

531 amino acids

MRHRGLGLAALLALLAAVAPRSSAAAGAALWPMPLSVKTSPRLLHLSRDNFSIGYGPSSTAGPTCSLLQEAFRRYHEYIFGFDKRQRRPAKPNSAIELQQLLVTVVLDSECDLFPNITSDESYTLLVKEPVAFLKANRVWGVLRGLETFSQLIYQDSYGTFTVNESDIIDSPRFPHRGILIDTARHFLPVKSILKTLDAMAFNKFNVLHWHIVDDQSFPYQSVTFPELSNKGSYSLSHVYTPNDVHTVIEYARLRGIRVIPEFDSPGHTQSWGKGQKDLLTPCYNEHKQSGTFGPINPILNSTYNFLSQFFKEVSMVFPDHFVHLGGDEVEFQCWESNPEIQGFMKQKGFGKDFRRLESFYLQKLLGIVSTVKKGSIVWQEVFDDHVKLLPGTIVQVWKNQVYTEELREVTAAGFPVILSAPWYLDWISYGQDWRNYYKVDPLHFDGSQEQKKLVIGGEACLWGEFVDATNLTPRLWPRASAVGERLWSPEDITSVGNAYNRLTVHRCRMVRRGISAEPLFTGYCDYEYKT

60.4 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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