Description
Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization.
Sequence
MALKDTGSGGSTILPISEMVSASSSPGAPLAAAPGPCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGDLPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEFFQLTDLVKLLSPKVTKQNSLNDECCQSDLEDNVSQGSSDALLLRGAAAGAPSGSGAHGVSGVVGGGSAPDKRSGFLTLGYRGSYTTVRDNQADAKFRRVARIMVCGRIALAKEVFGDTLNESRDPDRQPEKYTSRFYLKFTYLEQAFDRLSEAGFHMVACNSSGTAAFVNQYRDDKIWSSYTEYIFFRPPQKIVSPKQEHEDRKRDKVTDKGSESGTSCNELSTSSCDSHSEASTPQDNPANTQQAAAHQPNTLTLDRPSRKAPVQWMPPPDKRRNSELFQSLISKSRETNLSKKKVCEKLSVEEEMKKCIQDFKKIHIPDCFPERKRQWQSELLQKYGL
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service