Description
Required for cytoplasm to vacuole transport (Cvt) vesicles formation and mitophagy. Involved in binding of phosphatidylethanolamine to ATG8 and in recruitment of ATG8 and ATG5 to the pre-autophagosomal structure. Protects ATG8 from ARG4-mediated cleavage (By similarity).
Family
Belongs to the WD repeat SVP1 family.
Species
Candida albicans (strain SC5314 / ATCC MYA-2876)
Sequence
MVTINDLSFNPDYSSISVSTSDGFKIFNCEPFGEFYSSQESPLRKSISNSLEDSAGCQNPTHSKTDSQDTPARFPTAFLKMLFSTSLTIVVPQTQDNLGNRLLKIYNLKQNLKICELNFPSSIIDIKLNRKRLLVVLDTGQLYIYDLSCVRLLKILQLSFNEHDGDQKFIGDLSADDSSWLIIPVQSTNNQTDLLNAETGSQPSTPKLTPSDSVINTGSYSQYLEFTRNSSLSNLKKKNKLITLEDIKNDSEGWVVVYDTINLAPVVIFEAHHSTIARICISHRDNKVATASIKGTIIRIFDLKEFEGKVKVHKVKNLRRGHNLVKVNSLSFHNDNHILGCGSESNTIHLFKIHEEESDICTNENSEDRTNHNSDYEDSDGDTSKSSEDLNENLANLLISKPLDPVPMETEDKLSSSWFVKTKKLINNQYTSSIIKKLPYKDYFENLIWEPPQRSFAYIKLPEYAPHNEKDPRSNKVEIGFNNDLVFIASYHTGNFYQYQIPKQRGPVSSINEDDKREECSLISQFNLI
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service